•  
  •  
 

Abstract

Rheumatoid arthritis (RA), the most severe disease affect the joint and also the most common systemic autoimmune disease, affecting approximately 1% of the adult population .We investigate the serum levels of IL-10 and IL-6 in patients with Rheumatoid arthritis. About forty patients with Rheumatoid arthritis (30 female and 10 male) with ages ranged between (20-70) years were taken from (Al-Hussein Medical City/Kerbala).Control group consisted of 20 healthy people were free from signs and symptoms of arthritis were matched in age and gender with patients, and had no history for any arthritis problem .IL-10 (IL-10-EASIA Kit, DIAsource) (IL-6 ELISA kit ,immunotech),(Anti CC-P ELISA kit ,Medizym/Germany ) ,(RF ELISA Kit Euroimmun/Germany) were measured using the enzyme-linked immunosorbent assay (ELISA) method and CRP Vital kit using quantitative turbidimetry method . t-test , ANOVA and Pearson correlation were used to analyze results by using SPSS version 22. P-value ≤ 0.05 was considered significant. IL10,IL6,Anti-CCP,CRP and RF were increased significantly (p< 0.05) in patients compared with control group, So increasing of IL10,IL6,Anti-CCP,CRP and RF values at mild stage (41.4±1.3),sever stage(54.8±0.8),sever stage(952±114), server stage(49.3±1),sever stage (181.3±11) respectively increased significantly value (p< 0.05) among the stages, The results revealed no significant value (p>0.05) among the age groups and according the gender groups, While there were highly significant correlation (p< 0.05) found among studded parameters .

Article Type

Article

First Page

190

Last Page

196

Rights

Copyright (c) 2017 AL-QADISIYAH MEDICAL JOURNAL

Download

Share

COinS