Association of soluble HLA-G expressions and their roles on the Risk of Recurrent Pregnancy Loss in Iraqi Populations.

Authors

• zahraa Fadhil shaker, College of Dentistry, University of Al-Mustansiriyah, Baghdad, Iraq,Follow
• Manal Mohammed Kadhim, Department of Medical Microbiology, College of Medicine, University of Al-Qadisiyah, Al- Diwaniyah, IraqFollow

Abstract

Background: Human Leukocyte Antigen –G HLA-G is a non-classical HLA class molecule that productions a central part in immune tolerance at the motherly fetal interface. Aim of study: The current study was designed to examine the relationship of HLA-G gene expression among recurrent pregnancy loss in Iraq. Methods: An entire of 40 females with idiopathic RPL were comprised in the training who stayed known to infertility, gynecological and obstructs department in Baghdad Hospital City from the period between February /2022–October/ 2022, and further groups comprise of 40 actually healthy persons. A three ml of blood samples were collected for polymerase chain reaction for Real Time polymerase chain reaction expression analysis quantification of HLA-G and housekeeping gene (GAPDH) in blood patients and normal samples by utilizing of Real-Time PCR process. Results: The present outcomes suggest that decreased mean of Human leukocyte antigen-G (HLA-G) gene appearance in sick females with RPL in compared with healthy controls. Conclusion: The current results identified an relationship HLA-G gene appearance and RPL development.  

Article Type

Article

First Page

78

Last Page

84

Rights

Copyright (c) 2024 2024

Recommended Citation

shaker, zahraa Fadhil and Kadhim, Manal Mohammed (2026) "Association of soluble HLA-G expressions and their roles on the Risk of Recurrent Pregnancy Loss in Iraqi Populations.," Al-Qadisiyah Medical Journal: Vol. 20: Iss. 2, Article 4.
DOI: https://doi.org/10.28922/2312-7864.1666