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Abstract

Background;Studies showed that people with schizophrenia and other mental disorders have a higher incidence of exposure to T.gondii. The aim of the present paper is to estimate the rate of toxoplasmosis in schizophrenic patients.Methods;A total of (125) serum samples were studied.(100) patients from AL- Rashad Teaching Hospital compared with (25) healthy person as a control group; during the period from October 1,2009- March31,2010. All were male of age (20-55 years).Serum samples were tested by using ELISA Toxoplasma technique for Ab. detection (IgG and IgM) in addition to the serum testosterone concentration.Results;The results showed that 49% schizophrenics have IgG positive Toxoplasma ,6% have positive IgM and 4% have both IgG and IgM positive Toxoplasma .The risk of having schizophrenia in subjects with positive IgG Ab is 5 times higher than negative IgG Ab persons. The mean IgG Ab. titer was higher (1.1) in schizophrenics. The serum testosterone concentration was significant (6.1)in schizophrenics & was significantly higher in schizophrenics with positive IgG Ab.(7.1). No associations were found between toxoplasmosis and residence, smoking, alcohol consumption, educational level, history of contact with cats, or marital status.Conclusion;Schizophrenics have IgG positive Toxoplasma , high IgG Ab titre & serum testosterone concentration.

Article Type

Article

First Page

23

Last Page

32

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Copyright (c) 2017 AL-QADISIYAH MEDICAL JOURNAL

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