Minimally invasive surgery is a well known advantageous technique to all health systems, it is still possible to do minimal invasive technique, without using expensive equipments and its burden regarding; cost, maintenance and other disadvantages. This study was performed to compare minimally invasive surgery with classical traditional surgical technique in the aspects of reduced post-operative pain, shorter hospital stay and shorter convalescence period. In this study our cases underwent splenectomy through small incisions, which are almost equal to laparoscopic procedures and compared to equal number of cases underwent splenectomy through classical traditional technique. Decisions for splenectomy were made by physicians for a variety of well known disease status that complete cure or improvement will be gained by splenectomy. In this study, eighteen cases were studied, from which nine were males (mean age34.3±20.45) and nine were females (mean age=21.6±15.99). Nine of them were underwent splenectomy through minimally invasive incisions, the other group splenectomized through classical traditional incisions. The first group was discharged earlier; need much lesser narcotic medication and shorter convalescence period. In summary, compared to conventional classical method approach, Minimally Invasive Splenectomy is significantly facilitates the surgical procedure, reduces the risk and difficulty in the cases of splenomegaly. So this technique is more feasible and more effective than conventional clasical method for the removing of the splenomegaly.