A stereological study of a (middle piece) of ductus epididymis between normal adult human, bulls, rams, goats and buffalos was conducted using routine histological techniques. The following stereological parameters were determined; Stereocilia height, epithelial height, muscular wall thickness, lumen and tube diameters. The human epididymal stereocilia height is shorter than in goat only and higher than bulls and goats in both the epithelial height and muscular wall thickness. Human ductile diameter is smaller than in other animals. In conclusion, all human epididymal mid piece parameters in the present study differ significantly than in the other animals. Because human epididymis differs from other animals in fine structure and luminal contents, the present stereological study shows how structural data obtained from histological micrographs of the intact tissue and cells can be different between human and other animals mid peiece ductus epididymis.