Effect of evening primrose oil on primeralary blood coagulation investigation in male rabbits

Authors

  • Zena Hasan Sahib Babylon University / College of Medicine / Department of Pharmacology.
  • A.Razzak A.Latif Babylon University / College of Medicine / Department of Pathology.
  • Hussien Naji Abdullah Babylon University / College of Medicine / Department of Pharmacology.

DOI:

https://doi.org/10.28922/qmj.2011.7.12.47-56

Abstract

This study was performed to determine the effects of Evening primrose oil (EPO) on haemostatic parameters following 30 and 60 days administration of 90 mg/kg (EPO) to healthy male rabbits. The laboratory resulting in significant increase in Prothrombin time (PT), activated partial thromboplastin time (aPTT) assays (p<0.01), platelets count significantly decreased (p<0.01) at both times. While fibrinogen concentration are insignificantly decreased. These effects might be due to inactivation or inhibition of factors affecting coagulation.

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Published

2017-08-06

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Articles