A comparison study of saliva content before and after menopause

Abstract

Background:- In recent year saliva test is used instead of blood test in many medical fields for being more accurate and not invasive, for example it is used for evaluation of the benefit of using hormonal replacement therapy as treatment in post menopausal women.
Objective:- As relatively little is known about the effect of age on salivary composition, the aim of this study is to compare between saliva content before and after menopause for some of biochemical markers which are used for diagnosis ofmany medical condition and risk groups.
Methods :- Sixty-eight female were participate in this study, divided for two groups the first group consist of thirty-four female in premenopausal age and another thirty-four female represent the second group postmenopausal. Salivary samples were taken to assess urea level, glucose level, uric acid and cholesterol levels.

Results:- The results shows that urea level along with cholesterol levelwere significantly higher in postmenopausal women (P<0.01) while uric acid and glucose shows no significant difference (P>0.01).