Isolation and Identification of Bacteria from Patients with Transitional Cells Carcinoma of Urinary Bladder

Abstract

This study was conducted to isolate and identify the bacteria associated with tumor cells urinary bladder, in addition to investigate the histopathological changes in the urothelium of the urinary bladder. A total of 130 urine samples were taken and classified into three groups:(36 samples belong to patients with urinary bladder cancer, 64 samples of urinary tract infections(UTIs), and 30 samples as healthy group (control). These samples were collected from both sexes and different ages and lasted a period from January to June 2010 at Al-Diwaniyah Teaching Hospital. The results revealed that 32/36 (88.8%) of urinary bladder cancer samples were positive for bacterial growth, while was 64/64 (100%) for UTIs samples.The common isolated bacteria associated with tumor cells of urinary bladder and UTIs were similar and included six species (Escherichia coli , Staphylococcus aureus, Proteus morganii, P.mirabilis, Pseudomonas aeruginosa, and Klebsiella pneumonia. But the percentage of isolation was varied and the high percentage belonged to Escherichia coli (34.5%), and the lowest was Klebsiella pneumonia (6.2%).