The present study carried out on (249) cases of pregnant women deliver neonates baby with congenital malformations in ALZahra hospital for birth and childhood in AL- Najaf city, during the period (1/1/2005 to 31/12/2008). To determine the relationship between congenital malformations, age of pregnant women, neonate's sex and seasonal period during four years (2005, 206, 2007 and 2008). The results related biostatic significant information at (p>0.05) that the high rate of congenital malformations which occurred between (21-33 year) of the maternal ages. Our observations about year months which related to the malformations appearing the June and July in the years (2005, 2006 and 2007) was recorded highest percent of congenital malformations. From another hand, this present study revealed that high rate in female neonates than the male neonates when compared the neonates gander with congenital malformations.