Ceftriaxone Therapy Vs. Ciprofloxacin In Treatment Of Typhoid Fever In Adult Patients.

Abstract

Patients & method: 200 patients attending to the fever consultation unit from January 2008 to March 2009 in Al-dewania teaching hospital diagnosed on the base of clinical and rising widal O titer as typhoid fever patient were randomly equally divided into two groups G1 received ceftriaxone 1gm TID and G2 received ciprofloxacin 500 mg BID, every patient was closely followed by temperature chart for 7 days.
Result: 100% of G1 patients were afebrile (5) days after commencement of treatment while only 50% of G2 patients became afebrile (7) days after treatment.
Conclusion: this probably warning that resistant for ciprofloxacin is an evolving problem in our community and ceftriaxone is the drug of choice in treatment of typhoid fever.