In our study we monitor the gonadotopin therapy by ultrasound because serum oestradiol is not available in Basrah, and we investigate whether pelvic ultrasound alone suffices to control ovarian response to gonadotropin to induce ovulation. Real time ultrasound scanning of follicular development was performed for 35 patients receiving metrodin during 113 cycle. Twenty pregnancies were obtained resulting in a pregnancy rate of (57.1%); with (16) patients singletons, set of twins 4 (20%), with abortions 6(30%) and about patients 2 (5%) develops mild ovarian hyperstimulation syndrome (OHSS). So ultrasound alone can be used effectively to control gonadotropin therapy in the majority of cases.