Evaluation of Hepatitis B Virus Vaccination among Children in Al-Diawynia City

Abstract

This study attempts to determine the protective level of antibodies against hepatitis B surface antigen among vaccinated and unvaccinated children in Al-Diawynia city, age ranging 1- 10 year. A total of 220 blood samples have been collected and tested for detection of serological markers of hepatitis B virus (HBsAg, anti-HBs and anti- HBc). They included 150 children represented the vaccinated group and 70 children represented the unvaccinated group. Prevalence of anti-HBs was higher in vaccinated children 67.3% than in unvaccinated children 3.3%. Anti-HBc was not found in vaccinated children, while 4.2% in unvaccinated children. The distribution of protective level is divided to less than 10; 10 100; and 100-more than 500 mIU/ml among studies groups that have anti-HBs 14(9.3%); 34(22.6%); and 53(53.3%) of vaccinated and (0.0%); (1.4%); and 2(2.8%) of unvaccinated group. Finally, prevalence of protective antiHBs level according to the doses received by vaccinated group has revealed that 66% of those who received the three primary doses.