The Evaluation of High Density Lipoproteinscholesterol and Triglycerides on newely diagnosusis Gestatinal diabetes

Abstract

Many studies indicated that lipid profile risk factor for gestation diabetes mellitus (GDM), and the early detection of GDM may prevent or delay progression to type 2 diabetes mellitus. Detection of impaired gestation requires a test which is inconvenient to screen for this condition in clinical practice.This studies was aimed to assess these effects of high density lipoproteins-cholesterol (HDL-C) and triglycerides (TGs) on the manifestations of gestational diabetes mellitus (GDM).Materials and methods:-Twenty-four Pregnant women were preformed brief IGTT, (75g oral glucose tolerance test ) during period the August /2006 to October / 2007. They classified into three groups depending on the results of IGTT nets. 1.Group A: Normal Glucose Tolerance (NGT), (No.10).
2.Group B: Impaired gestation diabetes mellitus (IGDM), (No.7).
3.Group C: Gestational diabetes mellitus (GDM), (No.7).
HDL-c was showed a significant direct correlation with serum glucose assessed by 2h-OGTT (R2=0.173, 0.498, 0.723 for group A,B,
and C respectively). Gestation diabetes mellitus patients (GDM) showed direct correlation between HDL-C and serum glucose level. In addition, direct correlation between TG and serum glucose, but not reach to significant correlation.IGDM is associated with high density lipoprotein –cholesterol. The HDL-C and TG associated with risk for GDM and study this parameters help to prevent or delay GDM