Role of antioxidant therapy and cessation of smoking in treatment of infertile men

Abstract

Aim: To assess role of antioxidant therapy and cessation of smoking in infertile men .
Patients and Methods: This study was conducted at infertility unit at Al- Diwaniya gynecological hospital and private clinic from February 2012 to November 2013. Total number of patients was taken in study were 152. Thirty-five patients were secondarily infertile while 117 patients were primarily infertile. Range of duration of marriage was 1-8 years. Each man smoked from 15-40 cigarette per day for 2-15 years. The study was include patients presented with various seminal fluid analytic pictures (oligospermia, teratospermia, asthenospermia, OAT syndrome). Ninety patients were treated by antioxidants without cessation of smoking and 62 patients were treated by antioxidants with cessation of smoking.
Results: Regarding 27 asthenospermic ceased smoking patients (mean motility percentage before treatment is 16.4 and mean motility percentage after treatment is 30.1), 53 asthenospermic non ceased smoking patients (mean motility percentage before treatment is 15.3 and mean motility percentage after treatment is 31), 23 oligospermic ceased smoking patients (mean count per million before treatment is 6.3 and mean count per million after treatment is 15.2), 33 oligospermic non ceased smoking patients ( mean count per million is 6.4 and mean count per million after treatment is 9.2). regarding 5 teretospermic ceased smoking patients ( mean percentage of abnormal morphology before treatment is 1.8 and mean percentage of abnormal morphology after treatment is 12.4) and 11 teretospermic non ceased smoking patients(mean percentage of abnormal morphology before treatment is 1.7 and mean percentage of abnormal morphology after treatment is 5.6).
Conclusion: use of antioxidant and cessation of smoking in selected patients (normal serum hormones ) gives good improvement regarding motility and count of sperms