Measurement of glycosylated hemoglobin (HbA1C) remains the gold standard for the assessment of glycemic control in patients with type 2 diabetes. Recent investigations have studied the correlation between HbA1C levels and other aspects of glucose metabolism, specifically, postprandial glucose (PPG). The results suggest that PPG is also important to overall glycemic control and may be a better index of glucose regulation than no effect on FPG. Thus, all aspects of glucose metabolism appear to be clinically relevant and should be monitored for effective diabetes management. This study defines the clinical significance of postprandial hyperglycaemia regarding the development of diabetic nephropathy.