The level of serum magnesium activity in diabetes mellitus

Abstract

Objective: This study has been carried out to asses the activity of magnesium in the serum of patients with diabetes mellitus. Also the effect of glycemic control on magnesium levels was investigated .
Subjects and Methods: Ninety six patients with diabetes were enrolled in this study, together with 95 healthy subjects, matched for age and sex, who served as the control group. The serum levels of glucose, creatinine and magnesium were estimated in all subjects. Glycated hemoglobin (HbA1c) was estimated in diabetic patients and according to its level we classified the diabetic into 2 groups: Group 1: good glycemic control (57 patients). Group 2: poor glycemic control (39 patients) .
Results: Serum magnesium levels in diabetic group were found to be significantly lowered than in control group. We found a direct correlation between the Glycosylated hemoglobin and magnesium levels in our study .
Conclusion: The present study revealed that there is inverse relationship between the magnesium levels and the glucose homeostasis in diabetic patients. Furthermore, there is an affirmative effect for the glycemic control on the level of magnesium in diabetic patients.