Comparison of the effect of intravenous phenylephrin and ephedrine in treatment of hypotension after spinal anesthesia in cystoscopic surgery

Abstract

Background: Hypotension may accompany cystoscopy during spinal anesthesia for which a variety of measures have been considered and none of which has accepted wide agreement. For that reason the present study was conducted.  

Aim of the study: The objective was to study the changes in blood pressure during cystoscopy under spinal anesthesia in two groups of patients, one on ephedrine and the other on phenylephrin.

Patients and Methods: 100 patients were randomly assigned to two equal groups (n = 50). Randomization was done according to surgery list. Group 1 received ephedrine while group 2 received phenylephrine.

Results: Regarding systolic blood pressure, there was no significant difference in mean systolic blood pressure at baseline reading (P> 0.05); however, it was significantly higher in group 2 than in group 2 during follow up. Regarding diastolic blood pressure, there was no significant difference in mean diastolic blood pressure at baseline reading (P> 0.05); however, it was significantly higher in group 2 than in group 1 during follow up (P< 0.05). Regarding heart rate, there was no significant difference in mean heart rate at baseline reading (P> 0.05); however, it was significantly lower in group 2 than in group 1 during follow up (P< 0.05). 

Conclusion: Phenylephrine is better than ephedrine in controlling hypotension after spinal anesthesia in cystoscopy.