Hypercalcemia of malignancy

Abstract

Hypercalcemia is the most common life threatening metabolic disorder associated with neoplastic diseases, occurring in an estimated 10-20% of all persons with cancer.
Solid tumors (such as lung or breast cancer) as well as hematological malignancies (particularly multiple myeloma) are frequently associated with hypercalcemia.
Our study aims to detect the incidence of hypercalcemia in variable malignancies,130 patients, 67 female and 63 male who are presented to surgical and medical wards as a proved cases of malignancies by histopathological and/ or cytological examination were included in a prospective study in which serum was obtained with out use of tourniquet in supine position to measure total serum calcium, from all patients collected there were only 7 having hypercalcemia, 3 out of them were having breast cancer, 1 lung cancer, 1lymphoma, 1leukaemia and 1GIT cancer, thus from this study we concluded that the breast cancer is the most common tumor associated with hypercalcemia and this can accuse hypercalcemia in female more than male .