Therapeutic Consequences of microRNAs in Non-Small Cell Lung Cancer

Relation between transfection and CGIs methylation

Abstract

non-small cell lung cancer (NSCLC) is now moving beyond conventional chemotherapy with the advent of molecular-targeted therapies, and a key therapeutic strategy is inhibition of specific cytokines essential for tumor vascularization currently, angiogenesis quantification to assess and predict the efficacy of antiangiogenic drugs is mainly based on the evaluation of microvascular density. However, this procedure is highly invasive, and its association with the clinical outcome is uncertain in many tumor types, including NSCLC .