The effect of dates extracts were determined in human peripheral lymphocyte and monocyte cells using different concentrations of the extracts for three days- there term assay (MTT) was employed. There was no cytotoxic effect of the date extracts on human lymphocyte and monocyte cells. The results showed that the ideal concentrations of different date extracts have a protective effects of tamer (Barhi, Zahdi and Khistawy) to the lymphocyte and monocyte cells and may be that because these date extracts contain antioxidants in various type of dates.