The study was carried out to assess the effect of cinnamon oil on multi-drug resistant (MDR) strains of Staphylococcus aureus and Proteus mirabilis isolated from patient infected with otitis media. 50 specimens were collected at AL Hakeem Teaching Hospital in AL-Najaf governorate, 20 isolates were found to be Staphylococcus spp. and Proteus spp. on further studying for the species level only six of these isolates were found to be multi-drug resistant Staphylococcus aureus and Proteus mirabilis. The results of antibiotic sensitivity testing showed that most of these isolates were highly resistant (resistance percentage was 40-90%) for the used antibiotics. The antimicrobial effect of cinnamon oil on these isolates was tested via performing Disk Diffusion Method, Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) tests. The results showed a similarity in the antimicrobial actions between this oil and Ciprofloxacin antibiotic . The study concluded that Cinnamon Oil could be used as an effective antimicrobial even in case of difficult treated MDR Staphylococcus aureus and Proteus mirabilis.
