Use of isotretnion to decrease recurrence of chalazion

الملخص

Chalazion; is a nodular swelling occur as a result of accumulation of sebaceous secretions from abnormally functioned sebaceous glands situated in the eye lid causing ocular surface problems like dryness , irritation and refractive error due to pressure effect on the cornea in addition to cosmetic blemish ,topical treatment usually ineffective so we do surgical drainage . isotretnion is one derivatives of retinol a chemical name of the essential micronutrients vitamin A which have important role in human reproduction and development in addition this drug is well known by dermatologist and it is commonly used for treatment of seborrhea and other skin problems related to sebaceous glands. This present cross sectional study was done at AL-Diwaniah teaching hospital(ophthalmology department) at AL-Diwaniah city from September 2014- January 2017 ,110 patients (63 female,47 male) ,between 17-35years old are involved in this study attend ophthalmological department complaining from recurrent (or multiple) chalazion ,those patients had been given isotretnion orally a dose of 20 mg/day for10 - 12 weeks and followed for 6-12 months for re appearance of chalazion the result show decrease in the recurrence rate of chalazion with improvement in the tear film quality and ocular lubrication.