The present study was carried out to evaluate the relationship between uric acid level and some lipid profile for heart disease patients in Alnasseriya city in the sera samples of (75) patients, in addition to control group involving (45) apparently healthy. The current study included age ,weight , cholesterol, HDL , LDL, triglyceride ,and uric acid concentration. The study clarified no significant differences (p>0.05) in mean age of patients when compared with healthy control and high significant difference of mean weight between two groups (p<0.01).A highly significant elevated(P< 0.01 ) in the mean concentration of cholesterol, LDL and triglyceride in patients when compared with healthy control ,no significant (P> 0.05) in the mean concentration of HDL in both two groups .It also showed a highly significant increased (P<0.01) in the mean concentration of uric acid in heart disease patients when the results compared with the mean concentration of uric acid in healthy control . In the present study showed there was high significant correlation between uric acid and cholesterol, LDL (P<0.01) and significant correlation with triglyceride (P<0.05) but no significant correlation between uric acid and HDL (P>0.05 ).