Alga, bioactive compound, Candiasis, isolation and purification
Abstract
Bioactive chemical compound A1 was extracted, purified and identified from the algal culture of Nostoc linkia isolated from Basra Rivers in southern Iraq. The identification of the compound by using GC-mass was confronted. Solubility, toxicity, purity and the chemical formula and molecular weight of A1 compound were determined. The antimicrobial bioactivity of the purified compound against the bacterial strains Escherichia coli and Staphylococcus aureus and the dermatophytic fungus Candida albicans was tested by using a disk diffusion agar method. The Minimal Inhibitory Concentration (MIC) was also performed. The compound A1 has shown a broader activity spectrum against all the test organisms.
