Sera levels of Interleukin -6 in psoriatic patients in najaf city

Abstract

This work was done to evaluate IL-6 level , Total white blood cells count , Neutrophils and Eosinophils. Study group included (80) subjects were classified to two groups according to the severity of the psoriasis , mild which include 32 patients, their ages ranged between (9-40) years and sever group which include 48 patients , their ages ranged between (17-75 years) . The control group consist of (30) healthy volunteers , their ages ranged between (9-75) years no symptoms and with no history of psoriasis. Il-6 were estimated by kit The Biosoure Il-6 (EASIA) using a solid phase enzyme amplified sensitivity immunoassay (EASIA) performed on microtiterplate for serum in both mild and sever subjects The result revealed that The mean of IL-6 concentration was higher in sever psoriatic group (39.24 pg/ml) than mild psoriatic patients (20.98 pg /ml) with higher significantly at p<0.01 , while the levels of IL-6 in mild psoriatic group showed no significant differences as comparing with healthy control group (p>0.05); while Total white blood cells count of studied group were a significantly increased number of leukocyte in inflammatory skin and psoriasis patients, Neutrophils percentage of studied groups , the current study are similar to those of a significantly increased number of leukocytes in inflammatory skin and psoriasis patients , The mean value levels of patients were significantly higher than
those of control s(32.0) pg/ml and (12.64) pg/ml respectively at(p<0.01).