Lipid profile and pre – eclampsia

Abstract

Objective: To assess if there are changes in lipid profile in preeclampsia and if these changes can be used as marker of severity of the condition.
Study design: This study include 100 pregnant women divided into 3 groups.
1) 25 pregnant women with sever pre-eclampsia in the third trimester.
2) 25 pregnant women with mild-moderate pre-eclampsia in the third
trimester .
3) 50 apparently healthy pregnant women of comparable age &parity in the third trimester. All were investigated for serum lipid profile including
serum cholesterol(CH)
serum triglyceride(TG)
serum high density lipoprotein(HDL)
serum low density lipoprotein(LDL)
serum very low density lipoprotein(VLDL) Result: There was significant increase in serum TG ,VLDL and LDL level in women with pre -eclampsia than the control group and no significant difference in the serum cholesterol, while patient with preeclampsia had lower HDL level. When we compare patient with sever pre-eclampsia with patient with mild pre - eclampsia we found that women with sever pre -eclampsia has significantly higher level of TG and VLDL only.