In this study compare between the effect of aqueous extract of green tea and Hibiscus sabdroffira on some immunological parameters in vivo . Five ml of watery extract of these was given in animal orally for three weeks after five weeks animals were killed and pieces of intestinal tract was collected to study local immunity .Green tea extract was shown higher significant at P ≥0.005 in stimulation systemic and mucosal antibodies than Hibiscus extract . Hibiscus sabdroffira was shown increase in total protein and secretory immunoglobulins .Two plants were show effect on cellular immunity by increasing LIF mucosally but not systemically.