Study the role of Toxoplasma gondii, Cytomegalovirus and anti-phospholipids antibodies in cases of abortion among women in Hilla city

Abstract

This study was conducted to detect the role of T.gondii and CMV and the possible association between them in cases of abortion. Also the role of auto antibodies against phospholipids (APL) and it's association with the mentioned parasite and virus among women who have consulted the-Children and Maternity Hospital and General Teaching Hospital in AL-Hilla city, during the period from November 2006 to April 2007. Out of 120 samples, 50(41.66%) were positive for anti-Toxoplasma antibodies. While out of 44 sera, 35(79.5%) and 8(18.8%) were positive for anti-CMV IgG and IgM antibodies respectively. All control samples have been found to be negative for both Toxoplama and CMV. Twenty eight sera from aborted women (Some negative sera and others positive sera for anti-Toxoplasma and/or anti-CMV antibodies) were subtested for detection of anti-phospholipids (aPL) antibody by using ELISA, it was observed that only 3(10.7%) sera were positive.