Comparative Effectiveness Of Noninvasive Ventilation vs Invasive Mechanical Ventilation In Chronic Obstructive Pulmonary Disease Patients With Acute Respiratory Failure

Abstract

DESIGN OF STUDY: Retrospective cohort study.
DURATION: From 2011 - 2016
SETTING: Department of Anesthesiology, I.C.U., Aldiwaneya Teaching
Hospital.
PATIENTS AND METHODS: Over a period of 5 years, 200 patients with COPD exacerbated by acute respiratory failure, their ages range from 60-80 years, met the chriteria and admitted to the I.C.U. . 100 patients (50%) managed by invasive mechanical ventilation (IMV) (Group A) and the other 100 patients (50%) managed by noninvasive ventilation (NIV) (Group B), both groups with medical therapy (ABC) (Antibiotics,Bronchodilators,Corticosteroids).
RESULTS:
Group A: 78 patients (78%) died.
22 patients (22%) improved & discharged to the ordinary ward.
Group B: 73 patients (73%) had clinical biochemical improvement &
discharged well to the ordinary ward.
27 patients (27%) complicated & needed endotracheal
intubation & IMV, after 2-5 days, all died.
CONCLUSION: There is a significant outcome to the use of NIV vs IMV.