Estimation of Hepcidin Level and Its Correlation With Iron State in Pregnant Women

Abstract

This study aimed for determination of serum hepcidin level and its association with ?iron ?state in pregnant women with and without anemia. ?This study comprises ?86 pregnant women divided into two groups, the first ?group comprises 49 pregnant women without iron deficiency ?anemia?, the second group comprises 37 pregnant women with iron ?deficiency anemia. ?Blood was drawn from all pregnant women for determination of serum ferritin and hepcidin concentrations. The results establish a significant decrease in serum ferritin ?and hepcidin concentrations in pregnant women with anemia as paralleled with pregnant women without anemia. The outcomes of linear regression analysis demonstrate a significant positive association between serum ferritin ?and hepcidin concentrations in both study groups. In conclusion, measurement of serum hepcidin level is an important parameter for ?evaluation the iron state in pregnant women.