Thyroid dysfunction in patients with unstable angina

Abstract

Background 

Unstable angina has considerable effect on homeostasis of thyroid gland with consequences effect in form of mortality and morbidity. Thyroid hormone has an important effect in the cardiovascular system. Small changes of the thyroid hormone within the normal physiological response have been an adverse effect on cardiovascular results.

Aim of study

The study was designed to assess the profile of thyroid hormonein patients with unstable angina who wereadmitted to the Coronary care unit and toevaluate short term affection.

Patients and methods

An observational study was enrolled 40 patients were admitted to the CCU of AL-Diwanyia Teaching Hospital during period from 1st of March 2017 to the 30 of November 2017. Thyroid function tests (FT3, FT4, TSH) were done by ELISA method within 48 hours of admission.

Results

Sick euothyroid syndrome was observed in 42%, subclinical hypothyroidism in 35% and subclinical hyperthyroidism in 23% of patients with abnormal thyroid hormone profile in 65%. A higher prevalence of abnormal thyroid hormone profile (54%) was seen in elderly age group >60 years. 

Conclusion

There is  statistical significant value of thyroid dysfunction in patients with unstable angina and age groups >60 years, but withno significant difference regarding the gender.