Effect of Antibiotics Combination on Escherichia coli Contaminated Pacifier used by children suffering from diarrhea

Abstract

A total of eighty nine clinical samples were collected from pacifier of children  patients with age1-48 months from both gender complaining from diarrhea in Hilla city. 19 isolates of E.coli were isolated and identified according to their morphological properties( cultural  and microscopical) and biochemical tests and percentage (21.3%).Some clinical samples were showed Entamoeba histolytica ,Giardia lamblia and Trichomonas hominis  and Monilia. The susceptibility of the all current  isolates were carried out against 17 antibiotics, E.coli  isolates were very sensitive to meropenem and impenem ,and sensitive to sefitrixon ,amikacin, and ciprofloxacin ,while its resistance to others antibiotics were different. The minimum inhibitory concentrations(MIC) of some present isolates were higher.The combination of - lactam antibiotics (amoxicillin and cefotaxim)with quinolones(ciprofloxacin)from side and aminoglycoside (amikacin) from other side , demonstrated effective synergism of these mixtures anti multidrug resistance E.coli isolates