FS-Febrile seizure,IL-Interleuk An association of IL-6 and IL-10 serum levels with childhood febrile seizure Marwa .A. Raheem1 , Prof.Dr.Ibrahim A. Altamemi2 1-Department of Microbiology, College of Medicine, University of Al-Qadisiyah, Iraq, E-mail : med21.47@qu.edu.iq 2-Department of

Abstract

Abstract

Background_Febrile seizures are also-defined-as febrile..fits or febrile_ convulsions that-occur in children between/the ages_ of (6months_5years) who* have  a  fever  of  more,, than”38 degrees Celsius that are not associated with an intracranial reason/(like_as*an infection,, head.injury,or_epilepsy).

Objective- the aim of present study is to find out the Association of Inflammatory cytokines(IL-6, IL-10)serum levels with the onset of childhood febrile seizure.

Methods- A case control study was conducted using 40 patients with febrile seizures and 40 controls whose ages ranged from (5 months to 5 years) to determine association of serum IL-6,IL-10 levels with FS.

Under the supervision of a specialist pediatrician, samples were taken from Al-Zahra Maternity and Pediatric Hospital and out patient clinics for the time period of 8 October 2022 to 5 February 2023. In these locations, cases were diagnosed by pediatricians and the diagnosis was confirmed in accordance with the American Academy of Pediatrics (AAP) in 2011.the sociodermographic data are age,gender and family history of babies.

Results- A case-control study of 40 patient with FS and 40 control without FS revealed that the mean blood IL-6 , IL-10 levels in the patient group was significantly higher than in the control group.